SourceCF

Trio® Electronic Nebulizer

What you need to know:

Key Features
What Medications You Can Use
How It Works

How To Get A Trio®
Satisfied Customers
How To Clean It

Request Additional Info

Trio® reflects the three distinct advantages - a trio of advantages - for many patients who use the device.

Administration Time; reduced by up to 50% **
Volume Fill; reduced by up to 50% **
Freedom; increased as an ?external? AC power source is not required

Small, lightweight and silent, the Trio® combines two key nebulization principles - a high percentage of the delivered dose within the respirable range and a high output rate - to significantly reduce nebulization times.

Features include:

No compressor or propellant required

Small - fits in the palm of your hand
Lightweight - 9.5 ounces with batteries
Silent - no noise during treatments!

Fast Treatments Due to High Output Rate
(.73 ml/min)¹
High Delivered Dose (DD) 63% ₂ and High
Respirable Dose (RD)
Targeted Aerosol Delivery Due to Low Velocity
Aerosol and Narrow Geometric Standard
Deviation (GSD 1.51)¹
Low Residual Volume 0.7% ₃
Single Pass System, No Recirculation
During Nebulization
No Change In Concentration in Medication
Reservoir During Treatment
Inhalation by Spontaneous Breathing

Is It Available?

eFlow® SCF now known as Trio® was cleared for marketing and use by the FDA on May 5, 2004. It is available exclusively through The Respiratory Disease Network (RDN), a group of specialty pharmacies created to better address the specific needs of people affected by CF.

View Marketing Clearance

What Medications Can Be Used In It?

The FDA has cleared the Trio® for use "with patients for whom doctors have prescribed medication for nebulization. The Trio® is intended for adult and pediatric patients." For the medications you should use with the Trio®, please consult your physician.

View Intended Use

At the center of Trio® is eFlow® Technology, a novel technology that uses a vibrating stainless steel membrane to silently generate aerosol particles. As part of the Aerosol Head, this membrane has thousands of laser drilled holes which give uniform sized droplets. Patients receive the best of both worlds: a high respirable dose in a short amount of time.

Touchspray® Technology

Fig. 1 - eFlow® Technology

Before the patient inhales, a dense aerosol cloud forms in the Aerosol Chamber. Upon inhalation, this aerosol cloud (bolus) is delivered to the patient leading to high Delivered and Respirable Doses.

Fig. 2 - Trio®

Fig. 3 - Anatomy of the Trio®

How Can I Get A Trio®?

The Trio® is available with a prescription exclusively through The Respiratory Disease Network (RDN), a group of specialty pharmacies created to better address the specific needs of people affected by CF. Call 1-888-335-6946 and we will connect you with the RDN Pharmacy provider for your area. If you prefer, refer to the map below for the direct number to your Respiratory Disease Network Pharmacy provider.

We have surveyed over 120 patients using Trio®?Here is what they had to say!

80% are experiencing treatment times of under 6 minutes with the Trio®, compared to only 11% with their old nebulizers.
97% of those surveyed ranked a shorter treatment time as a "very important" or "somewhat important" feature.
96% of those surveyed ranked portability of the nebulizer / compressor system as a "very important" or "somewhat important" feature.

The eflow is the best device to come along in years. It makes doing my daughter's nebulized meds so much easier. Instead of spending 30 minutes to an hour every morning and evening we can do everything in 10 minutes or less - If we are running late, we can take the eflow with us in the car. It is a device I would highly recommend to anyone.
- J.S. of Tucker, GA (11-29-05)

SourceCF is among the best and easiest to work with in getting supplies and a new compact eflow nebulizer. They rushed to get me everything I needed for a trip to the far side of the planet in New Zealand. The equipment worked great. It was lighter, more compact, faster, and more efficient than anything I have ever used. The customer service is the friendliest and easiest to work with, when reordering meds. I love them.
- S.H. of Atlanta, GA (10-24-05)

I've had my E-Flow machine now for about four months and love it! It makes my breathing treatments so much easier and still delivers a powerful dose of medication! It is also lightweight and portable making it very easy to travel with - thank you!!
- H.H of Marietta, GA (2-13-06)

Trio® was formerly known as eFlow®SCF

Footnotes:

S. Seeman, R.Waldner,M. Hug,M. Knoch, M. Keller. A New Electronic Inhaler (eFlow®SCF) to Improve Delivery of Inhaled Medications in CF Patients. Abstract 1892, American Thoracic Society Meeting, Orlando, Florida, May 2004.
M. Borgschulte, M. Germer, M. Hug,M. Keller,M. Knoch, R. Stangl. Means to Optimize Drug Delivery for a Novel Electronic Inhaler (eFlow®SCF). Respiratory Drug Delivery IX.
M. Borgschulte, R. Stangl, M. Keller, M. Knoch. Improvement of Pulmonary Drug Delivery by eFlow, A Novel Electronic Inhaler Making Use of a Vibrating Membrane Principle. European Respiratory Society Annual Congress, Poster 2573. Vienna, Austria, September 27-October 1, 2003
** Versus a jet nebulizer, when the Physician's goal is to deliver an equivalent respirable dose.